首页> 外文OA文献 >Randomized study of chemotherapy and surgery versus radiotherapy for stage IIIA non-small-cell lung cancer: a National Cancer Institute of Canada Clinical Trials Group Study.
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Randomized study of chemotherapy and surgery versus radiotherapy for stage IIIA non-small-cell lung cancer: a National Cancer Institute of Canada Clinical Trials Group Study.

机译:IIIA期非小细胞肺癌化学疗法,手术疗法与放射疗法的随机研究:加拿大国家癌症研究所临床试验小组研究。

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摘要

Thirty-one patients with stage IIIA (N2) non-small-cell lung cancer were randomized to receive radiotherapy alone or chemotherapy with cisplatin and vinblastine followed by surgery. Response rates to induction chemotherapy and radiotherapy were 50% and 53.3% respectively. Complete surgical resection was possible for 62.5% of patients. Median survival times were 16.2 and 18.7 months for radiotherapy alone and chemotherapy-surgery respectively (P = Ns), with no long-term improvement in survival seen with combined-modality treatment.
机译:随机将31例IIIA期(N2)非小细胞肺癌患者单独接受放疗或采用顺铂和长春碱化疗,然后进行手术。诱导化疗和放疗的缓解率分别为50%和53.3%。 62.5%的患者可以进行完全手术切除。单纯放疗和化疗手术的中位生存时间分别为16.2和18.7个月(P = Ns),联合治疗未见长期生存的改善。

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